Dr Helen Denton

Research Fellow

BMS Level 3 Annex
tel. 01334 46 3417
fax. 01334 462595
hd17@st-andrews.ac.uk

 

Publications

Serrán-Aguilera, L, Denton, H, Rubio-Ruiz, B, López-Gutiérrez, B, Entrena, A, Izquierdo, L, Smith, TK, Conejo-García, A & Hurtado-Guerrero, R 2016, 'Plasmodium falciparum choline kinase inhibition leads to a major decrease in phosphatidylethanolamine causing parasite death' Scientific Reports, vol 6, 33189. DOI: 10.1038/srep33189, 10.1038/srep33189
Richmond, GS, Gibellini, F, Young, SA, Major, L, Denton, H, Lilley, A & Smith, TK 2010, 'Lipidomic analysis of bloodstream and procyclic form Trypanosoma brucei' Parasitology, vol 137, no. 9, pp. 1357-1392. DOI: 10.1017/S0031182010000715
Denton, H, Fyffe, S & Smith, TK 2010, 'GDP-mannose pyrophosphorylase is essential in the bloodstream form of Trypanosoma brucei' Biochemical Journal, vol 425, no. 3, pp. 603-614. DOI: 10.1042/BJ20090896
Niewiadomski, S, Beebeejaun, Z, Denton, H, Smith, TK, Morris, RJ & Wagner, GK 2010, 'Rationally designed squaryldiamides - a novel class of sugar-nucleotide mimics?' Organic & Biomolecular Chemistry, vol 8, no. 15, pp. 3488-3499. DOI: 10.1039/c004165c
Smith, TK, Young, BL, Denton, H, Hughes, DL & Wagner, GK 2009, 'First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness' Bioorganic and Medicinal Chemistry Letters, vol 19, no. 6, pp. 1749-1752. DOI: 10.1016/j.bmcl.2009.01.083
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