University of St Andrews
 
 

Dr Laura Aitken
Research Fellow

Medical and Biological Sciences Building
University of St Andrews
North Haugh
St Andrews
Fife
KY16 9TF
UK

 

Publications

Hroch, L, Guest, P, Benek, O, Soukup, O, Janockova, J, Dolezal, R, Kuca, K, Aitken, L, Smith, TK, Gunn-Moore, F, Zala, D, Ramsay, RR & Musilek, K 2017, 'Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment' Bioorganic & Medicinal Chemistry, vol 25, no. 3, pp. 1143-1152. DOI: 10.1016/j.bmc.2016.12.029
Benek, O, Hroch, L, Aitken, L, Dolezal, R, Guest, P, Benkova, M, Soukup, O, Musil, K, Hughes, R, Kuca, K, Smith, TK, Gunn-Moore, F & Musilek, K 2017, '6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: design, synthesis and in vitro evaluation' Medicinal Chemistry, vol 13. DOI: 10.2174/157340641366170109142725
Hroch, L, Benek, O, Guest, P, Aitken, L, Soukup, O, Janockova, J, Musil, K, Dohnal, V, Dolezal, R, Kuca, K, Smith, TK, Gunn-Moore, FJ & Musilek, K 2016, 'Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer’s disease treatment' Bioorganic and Medicinal Chemistry Letters, vol 26, no. 15, pp. 3675-3678. DOI: 10.1016/j.bmcl.2016.05.087
Aitken, L, Quinn, SD, Perez-Gonzalez, DC, Samuel, IDW, Penedo-Esteiro, JC & Gunn-Moore, FJ 2016, 'Morphology-specific inhibition of β-amyloid aggregates by 17β-hydroxysteroid dehydrogenase type 10' ChemBioChem, vol 17, no. 11, pp. 1029-1037. DOI: 10.1002/cbic.201600081
Benek, O, Aitken, L, Hroch, L, Kuca, K, Gunn-Moore, FJ & Musilek, K 2015, 'A direct interaction between mitochondrial proteins and amyloid-β peptide and its significance for the development and treatment of Alzheimer’s disease' Current Medicinal Chemistry, vol 22, no. 9, pp. 1056-1085. DOI: 10.2174/0929867322666150114163051
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