Dr Magnus Alphey

X-Ray Facility Manager

BMS Level 2 (BSRC annex)
tel. 01334 467257/7250
fax. 01334 462595
msa31@st-andrews.ac.uk

 

Publications

Stroek, R, Ge, Y, Talbot, PD, Glok, MK, Bernas, KE, Thomson, CM, Gould, ER, Alphey, MS, Liu, H, Florence, GJ, Naismith, JH & da Silva, RG 2017, 'Kinetics and structure of a cold-adapted hetero-octameric ATP phosphoribosyltransferase' Biochemistry, vol 56, no. 5, pp. 793-803. DOI: 10.1021/acs.biochem.6b01138
Alphey, MS, Pirrie, L, Torrie, LS, Abdelli Boulkeroua, W, Gardiner, M, Sarkar, A, Maringer, M, Oehlmann, W, Brenk, R, Scherman, MS, McNeil, M, Rejzek, M, Field, RA, Singh, M, Gray, D, Westwood, NJ & Naismith, J 2013, 'Allosteric Competitive Inhibitors of the Glucose-1-phosphate Thymidylyltransferase (RmlA) from Pseudomonas aeruginosa' ACS Chemical Biology, vol 8, no. 2, pp. 387-396. DOI: 10.1021/cb300426u
Moynie, L, Leckie, SM, McMahon, SA, Duthie, FG, Koehnke, A, Taylor, JW, Alphey, MS, Brenk, R, Smith, AD & Naismith, JH 2013, 'Structural insights into the mechanism and inhibition of the beta-Hydroxydecanoyl-Acyl carrier protein dehydratase from pseudomonas aeruginosa' Journal of Molecular Biology, vol 425, no. 2, pp. 365-377. DOI: 10.1016/j.jmb.2012.11.017
Moynie, L, Schnell, R, McMahon, SA, Sandalova, T, Abdelli Boulkeroua, W, Schmidberger, JW, Alphey, M, Cukier, C, Duthie, F, Kopec, J, Liu, H, Jacewicz, A, Hunter, WN, Naismith, JH & Schneider, G 2013, 'The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery' Acta Crystallographica. Section F, Structural biology and crystallization communications , vol 69, no. 1, pp. 25-34. DOI: 10.1107/S1744309112044739
Byres, E, Alphey, MS, Smith, TK & Hunter, WN 2007, 'Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity' Journal of Molecular Biology, vol 371, no. 2, pp. 540-553. DOI: 10.1016/j.jmb.2007.05.094
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Dr Magnus Alphey
Biomolecular Sciences Building
University of St Andrews
North Haugh
St Andrews
Fife
KY16 9ST
UK

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