Mr Patrick Guest

Research Fellow

MBS 137
tel. 01334 461863/1864
fax. 01334 462595



Benek, O, Hroch, L, Aitken, L, Dolezal, R, Guest, P, Benkova, M, Soukup, O, Musil, K, Hughes, R, Kuca, K, Smith, TK, Gunn-Moore, F & Musilek, K 2017, '6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: design, synthesis and in vitro evaluation' Medicinal Chemistry, vol 13, no. 4, pp. 345-358. DOI: 10.2174/1573406413666170109142725
Hroch, L, Guest, P, Benek, O, Soukup, O, Janockova, J, Dolezal, R, Kuca, K, Aitken, L, Smith, TK, Gunn-Moore, F, Zala, D, Ramsay, RR & Musilek, K 2017, 'Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment' Bioorganic & Medicinal Chemistry, vol 25, no. 3, pp. 1143-1152. DOI: 10.1016/j.bmc.2016.12.029
Hroch, L, Benek, O, Guest, P, Aitken, L, Soukup, O, Janockova, J, Musil, K, Dohnal, V, Dolezal, R, Kuca, K, Smith, TK, Gunn-Moore, FJ & Musilek, K 2016, 'Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer’s disease treatment' Bioorganic and Medicinal Chemistry Letters, vol 26, no. 15, pp. 3675-3678. DOI: 10.1016/j.bmcl.2016.05.087