Prof Terry Smith

Professor

BMS B310
tel. 01334-463412
fax. 01334 462595
tks1@st-andrews.ac.uk

Professor Terry K. Smith is a reader in both the school of chemistry and the school of biology at the University of St Andrews, Scotland. His research utilizes a wide range of disciplines to genetically and chemically validate drug targets involved in lipid metabolism of protozoan parasites that cause neglected tropical diseases such as African sleeping sickness and American Trypanosomiasis.

An interview with Terry by the International Innovation magazine can be found here.

 

Publications

Menzies, SK, Tulloch, LB, Florence, GJ & Smith, TK 2018, 'The trypanosome alternative oxidase: a potential drug target?' Parasitology, vol 145, no. 2, pp. 175-183. DOI: 10.1017/S0031182016002109
Gaspar, L, Coron, RP, Kongthoo Lin, P, Costa, DM, Perez-Cabezas, B, Tavares, J, Roura-Ferrer, M, Ramos, I, Ronin, C, Major, LL, Ciesielski, F, Pemberton, IK, MacDougall, J, Ciapetti, P, Smith, TK & Cordeiro-da-Silva, A 2018, 'Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease' PLoS Neglected Tropical Diseases, vol 12, no. 1, e0006180. DOI: 10.1371/journal.pntd.0006180
Fraser, AL, Menzies, SK, King, EFB, Tulloch, L, Gould, ER, Zacharova, M, Smith, TK & Florence, GJ 2018, 'Design and synthesis of broad spectrum trypanosomatid selective inhibitors' ACS Infectious Diseases, vol In press. DOI: 10.1021/acsinfecdis.7b00187
Tulloch, LB, Menzies, SK, Coron, RP, Roberts, MD, Florence, GJ & Smith, TK 2018, 'Direct and indirect approaches to identify drug modes of action' IUBMB Life, vol 70, no. 1, pp. 9-22. DOI: 10.1002/iub.1697
Gould, ER, King, EFB, Menzies, SK, Fraser, AL, Tulloch, LB, Zacharova, MK, Smith, TK & Florence, GJ 2017, 'Simplifying nature: towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins' Bioorganic & Medicinal Chemistry, vol 25, no. 22, pp. 6126-6136. DOI: 10.1016/j.bmc.2017.01.021
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