Prof Terry Smith

Professor

BMS B310
tel. 01334-463412
fax. 01334 462595
tks1@st-andrews.ac.uk

Professor Terry K. Smith is a reader in both the school of chemistry and the school of biology at the University of St Andrews, Scotland. His research utilizes a wide range of disciplines to genetically and chemically validate drug targets involved in lipid metabolism of protozoan parasites that cause neglected tropical diseases such as African sleeping sickness and American Trypanosomiasis.

An interview with Terry by the International Innovation magazine can be found here.

 

Publications

Hroch, L, Guest, P, Benek, O, Soukup, O, Janockova, J, Dolezal, R, Kuca, K, Aitken, L, Smith, TK, Gunn-Moore, F, Zala, D, Ramsay, RR & Musilek, K 2017, 'Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment' Bioorganic & Medicinal Chemistry, vol 25, no. 3, pp. 1143-1152. DOI: 10.1016/j.bmc.2016.12.029
Sayer, LH, Florence, GJ & Smith, T 2017, 'A biocatalytic approach towards the stereoselective synthesis of protected inositols' Reaction Chemistry and Engineering, vol 2, no. 1, pp. 44-49. DOI: 10.1039/c6re00175k
Gould, ER, King, EFB, Menzies, SK, Fraser, AL, Tulloch, LB, Zacharova, MK, Smith, TK & Florence, GJ 2017, 'Simplifying nature: towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins' Bioorganic & Medicinal Chemistry, vol In press. DOI: 10.1016/j.bmc.2017.01.021
Farine, L, Jelk, J, Choi, J-Y, Voelker, DR, Nunes, J, Smith, TK & Bütikofer, P 2017, 'Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei' Molecular Microbiology. DOI: 10.1111/mmi.13637
Benek, O, Hroch, L, Aitken, L, Dolezal, R, Guest, P, Benkova, M, Soukup, O, Musil, K, Hughes, R, Kuca, K, Smith, TK, Gunn-Moore, F & Musilek, K 2017, '6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: design, synthesis and in vitro evaluation' Medicinal Chemistry, vol 13. DOI: 10.2174/157340641366170109142725
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