Prof Terry Smith


BMS B310
tel. 01334-463412
fax. 01334 462595

Professor Terry K. Smith is a reader in both the school of chemistry and the school of biology at the University of St Andrews, Scotland. His research utilizes a wide range of disciplines to genetically and chemically validate drug targets involved in lipid metabolism of protozoan parasites that cause neglected tropical diseases such as African sleeping sickness and American Trypanosomiasis.

An interview with Terry by the International Innovation magazine can be found here.



Farine, L, Jelk, J, Choi, J-Y, Voelker, DR, Nunes, J, Smith, TK & Bütikofer, P 2017, 'Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei' Molecular Microbiology, vol 104, no. 3, pp. 412-427. DOI: 10.1111/mmi.13637
Aitken, L, Baillie, G, Pannifer, A, Morrison, A, Jones, PS, Smith, TK, McElroy, SP & Gunn-Moore, FJ 2017, 'In vitro assay development and HTS of small molecule human ABAD/17β-HSD10 inhibitors as therapeutics in Alzheimer’s Disease' SLAS Discovery, vol 22, no. 6, pp. 676-685. DOI: 10.1177/247255521769796
Greaves, J, Munro, KR, Davidson, SC, Riviere, M, Wojno, J, Smith, TK, Tomkinson, NCO & Chamberlain, LH 2017, 'Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry' Proceedings of the National Academy of Sciences of the United States of America, vol 114, no. 8, pp. E1365-E1374. DOI: 10.1073/pnas.1612254114
Hroch, L, Guest, P, Benek, O, Soukup, O, Janockova, J, Dolezal, R, Kuca, K, Aitken, L, Smith, TK, Gunn-Moore, F, Zala, D, Ramsay, RR & Musilek, K 2017, 'Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment' Bioorganic & Medicinal Chemistry, vol 25, no. 3, pp. 1143-1152. DOI: 10.1016/j.bmc.2016.12.029
Sayer, LH, Florence, GJ & Smith, T 2017, 'A biocatalytic approach towards the stereoselective synthesis of protected inositols' Reaction Chemistry and Engineering, vol 2, no. 1, pp. 44-49. DOI: 10.1039/c6re00175k
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